Publications

Neuron

DOI: 10.1016/j.neuron.2021.09.010

The convergent evolution of the fly and mouse olfactory system led us to ask whether the anatomic connectivity and functional logic of olfactory circuits would evolve in artificial neural networks trained to perform olfactory tasks.

Current Opinion in Neurobiology

DOI: 10.1016/j.conb.2021.10.010

Neural circuits and artificial neural networks (ANNs) process information by constructing and manipulating highly distributed representations [1, 2, 3, 4].

PLOS Computational Biology

DOI: 10.1371/journal.pcbi.1009439

We introduce a new video analysis tool that combines the output of supervised pose estimation algorithms with unsupervised dimensionality reduction methods to produce interpretable, low-dimensional representations of behavioral videos that extract more information.

STAR Protocols

DOI: 10.1016/j.xpro.2021.100667

Bioluminescent optogenetics (BL-OG) allows activation of photosensory proteins, such as opsins, by either fiberoptics or by administering a luciferin. BL-OG thus confers both optogenetic and chemogenetic access within the same genetically targeted neuron.

PLOS Computational Biology

DOI: 10.1371/journal.pcbi.1009205

The Drosophila mushroom body exhibits dopamine dependent synaptic plasticity that underlies the acquisition of associative memories. Recordings of dopamine neurons in this system have identified signals related to external reinforcement such as reward and punishment.

eLife

DOI: 10.7554/elife.56265

We present a novel technique, emergent property inference that brings the modern probabilistic modeling toolkit to theoretical neuroscience. When theorizing circuit models, theoreticians predominantly focus on reproducing computational properties rather than a particular dataset.

Biomedical Optics Express

DOI: 10.1364/boe.427979

Optical coherence microscopy (OCM) uses interferometric detection to capture the complex optical field with high sensitivity, which enables computational wavefront retrieval using back-scattered light from the sample.

Journal of Neurophysiology

DOI: 10.1152/jn.00120.2021

Control of adaptive walking requires the integration of sensory signals of muscle force and load. We have studied how mechanoreceptors (tibial campaniform sensilla) encode “naturalistic” stimuli derived from joint torques of stick insects walking on a horizontal substrate.

Neuron

DOI: 10.1016/j.neuron.2021.05.019

Humans and other animals can identify objects by active touch, requiring the coordination of exploratory motion and tactile sensation. Both the motor strategies and neural representations employed could depend on the subject’s goals.