Publications

Graphs in Biomedical Image Analysis and Integrating Medical Imaging and Non-Imaging Modalities

In this work, we consider the problem of predicting the course of a progressive disease, such as cancer or Alzheimer’s. Progressive diseases often start with mild symptoms that might precede a diagnosis, and each patient follows their own trajectory.

arXiv

Traditional deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair.

Nature

DOI: 10.1038/s41586-018-0511-6

The naturally occurring channelrhodopsin variant anion channelrhodopsin-1 (ACR1) exhibits large light-gated anion conductance and high anion selectivity when expressed in heterologous settings.

Journal of Neuroscience Research

DOI: 10.1002/jnr.24313

Science

DOI: 10.1126/science.aat5691

Retrieving high-content gene-expression information while retaining three-dimensional (3D) positional anatomy at cellular resolution has been difficult, limiting integrative understanding of structure and function in complex biological tissues.

Journal of the Optical Society of America A

DOI: 10.1364/josaa.35.001438

We derive analytic expressions for the three-dimensional coherent transfer function and coherent spread function for coherent holographic image reconstruction by phase transfer microscopy with monochromatic and broadband illumination sources.